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pentobarbital will reduce the extent or impact of triazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will reduce the level or effect of oliceridine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. If coadministration with a CYP3A4 inducer is critical, consider ris